Diagnostic consequences of cytomegalovirus glycoprotein B polymorphisms.
نویسندگان
چکیده
Failure of a cytomegalovirus (CMV) real-time PCR assay targeting glycoprotein B (gB) was investigated. A multiplex assay targeting gB and immediate-early 2 (IE2) genes showed discordant results (gB negative and IE positive or a >10-fold-higher viral load with IE primers) in saliva from 14.6% of CMV-infected newborns. Sequencing revealed 3 patterns of gB variations.
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ورودعنوان ژورنال:
- Journal of clinical microbiology
دوره 49 8 شماره
صفحات -
تاریخ انتشار 2011